I finally got to a 100 yard range with my 4095 classic. Per previous thread here
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I made a DIY rail-over-irons adapter and put a cheap red-dot on it. Zeroed it as best I could off-hand standing at 18 yards, and there it sat for a few months. Here's the result at 100 yards without touching the sights:
]http://i902.photobucket.com/albums/ac222/museummaster/IMG_1293.jpg]
I made a DIY rail-over-irons adapter and put a cheap red-dot on it. Zeroed it as best I could off-hand standing at 18 yards, and there it sat for a few months. Here's the result at 100 yards without touching the sights:

I shot 20 rounds with irons (all in the lower right quadrant), and 40 rounds with the red-dot (I counted 38 or 39 in the upper right quadrant). Ammo was 180 gr Blazer aluminum. Had my first malf early (stove pipe), which may have been because I was shooting seated and had the mag resting on the table.
The red-dot has a fairly substantial standoff distance above the barrel, and zeroing it at 18 yards almost certainly puts the red-dot sight axis crossing the bullet path at a fairly significant angle. I'm pretty sure this is why the red-dot group cluster about 10" above the iron sight "group."
The "groups," if you can call them that, have about 80% inside 6". Some of that is undoubtedly me, as I wasn't using a rest (other than right elbow on the table). I should run the geometry calculations to see if the 10" offset between groups is consistent with the difference in standoff of the irons and the red-dot.
Conclusion is that a decent group can be shot with .40S&W at 100 yards, but might not be accurate enough for hunting. I have no idea what the ballistics are at that range, , but it doesn't seem that bullet drop is a huge factor.