Win 231/HP38 for what I presently load. .380/9mm/45ACP. I've only been reloading for a year and have opted not to experiment with other powders. This works fine, is affordable and my paper zombies at the local indoor range don't seem to mind much. lol.
I have no doubt that there are many other makes/types out there that might be better for a specific pistol caliber, but for my present needs I'm not much motivated to change - besides I bought a big jug of the Win231 and until I use it up I'm buying primers and bullets instead.