When I started reloading, I was all about Hodgdon/Winchester/IMR because, well, that's what the gun store sold, and it worked. The more I loaded, the more I branched out and tried other powders. My first foray into Alliant was Bullseye, because "that's what you use with .38 Special Wadcutters". Turns out, you can use it for a lot more. Later, I bought a pound of Unique for .32 S&W Long. It worked great for that, .32 H&R Mag., .38 Special, .357 Mag., .30-30 cast, 8mm Mauser cast, and just about anything else I've loaded. You'd be hard pressed to find a caliber and bullet that you can't find a Unique load for. Is it magic Unicorn dust? No, but it works... for nearly everything.